SIMULATION OF THE MECHANISM ANTIRADICAL PROCESSES AT THE NANOSCALE INVOLVING MELATONIN IN BIOLOGICAL SYSTEMS

Authors

  • Alyona Prokopenko Poltava National Technical University named after Yuriy Kondratyuk http://orcid.org/
  • Veniamin Solovev Poltava National Technical University named after Yuriy Kondratyuk http://orcid.org/0000-0002-0805-966X
  • Tatyana Kuznecova Poltava National Technical University named after Yuriy Kondratyuk http://orcid.org/0000-0002-1918-9436
  • Natalya Rogova Poltava National Technical University named after Yuriy Kondratyuk http://orcid.org/

DOI:

https://doi.org/10.30889/2523-4692.2019-09-01-004

Keywords:

free radicals, superoxide-anion-radical, melatonin.

Abstract

Based on the results of ab initio quantum chemical calculations of the interaction of the molecule MLT superoxide anion radical (•OOˉ) was studied antiradical properties of antioxidants. Established the most probable active sites of interaction of the mol

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References

Беленичев И.Ф.Регуляция антиоксидантного гомеостаза и системы детоксикации организма гормоном мелатонином. Роль мелатонин-зависимых рецепторов в реализации этой функции / И.Ф. Беленичев, Ю.И. Губский, Е.Л. Левицкий //Соврем. проблемы токсикологии. − 2003. − № 2. − С.2–-16.

Малиновская Н.К. Роль мелатонина в организме человека /Н.К Малиновская // Клиническая медицина.− 1998.− №10. − C. 15–22.

Dawson D. Integrating the actions of melatonin on human physiology /D.Dawson // Ann. Med. − 1998.− V.30.− P. 95–102.

Кветная Т.В. Мелатонин: Роль и значение в возрастной патологии /Т.В. Кветная − СПб.: ВМЕДА, 2003. − 256 с.

Russel J.Melatonin: Lowering the High Price of Free Radicals / J. Russel //News Physiol. Sci. – 2000. – V.15. – P. 246–250.

Alex A. Granovsky. Firefly and PC GAMESS /Firefly version 8.0.1. [Electronic resource]. − Access mode //http://classic.chem.msu.su /gran/games/forum/ discussion.html.

References

Belenychev I.F., Gubskiy Y.I., Levitsky E.L. Regulation of antioxidant homeostasis and detoxification system of the body of the hormone melatonin. The role of melatonin-dependent receptors in the realization of this function. Modern problems of toxicology.2003; (2):2–-16. (In Russian).

Malynovskaya N.K. The role of melatonin in the human body. Klynycheskaya medytsyna. 1998; (10): 15–22. (In Russian).

Dawson D. Integrating the actions of melatonin on human physiology. Ann. Med. 1998; 30: 95–102.

Kvetnaya T.V. Melatonin: role and importance in age-related pathology. SPb.: VMEDA. 2003; 256 р. (In Russian).

Russel J.Melatonin: Lowering the High Price of Free Radicals. News Physiol. Sci. 2000; 15:246–250.

Alex A. Granovsky. Firefly and PC GAMESS /Firefly version 8.0.1. [Electronic resource]. − Access mode //http://classic.chem.msu.su /gran/games/forum/ discussion.html

Published

2019-10-17

How to Cite

Прокопенко, А., Соловьев, В., Кузнецова, Т., & Рогова, Н. (2019). SIMULATION OF THE MECHANISM ANTIRADICAL PROCESSES AT THE NANOSCALE INVOLVING MELATONIN IN BIOLOGICAL SYSTEMS. Modern Scientific Researches, 1(09-01), 56–60. https://doi.org/10.30889/2523-4692.2019-09-01-004

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